Mesothelioma Attorney San Diego - Mesothelioma affects three main organs of the body. Affected areas, including the lungs and digestive system and heart. The most common form of mesothelioma is pleural mesothelioma. The second most common form of mesothelioma is peritoneal mesothelioma which destroys the stomach and intestines. So-called pericardial mesothelioma is a rare form of mesothelioma that attacks the lubricating film in circulation in the heart.